Oxycodone 80 mg is made by utilizing a semi-synthetic opioid, Oxycodone , an analgesic derivative from Thebaine. Thebaine is a natural alkaloid extracted from papaver somniferum (poppy seeds) resins. The oxygen drug is on the essential medicines list of the WHO World Health Organization as it is beneficial to moderate relief to severe persistent pain when non-opioid remedies and medicines fail. This is regulated under the Controlled Substances Act Schedule II. How Does Oxygen 80mg function? Oxygen 80 extended-release works by activating the opioid receptor. It is an agonist(a chemical that works as a receptor activator) of μ opioid receptor (MOR). It is called extended release as it is metabolized at a slower speed. After binding Oxycodone with MOR, a g-protein complex is released in inhibiting the release of neurotransmitters. That is how it relieves the pain. Uses of Oxycodone 80mg: Oxy pills come in two release schemes namely immediate release and extended release. Immediate release is used for acute or chronic moderate to severe pain while extended release is recommended when the patient requires long-term opioid treatment and other alternatives are not sufficient. Medical practitioners and doctors sometimes recommend oxycodone in combination with naloxone. This off-label prescription is helpful in severe restless legs syndrome. Note: Children in the US can be prescribed oxycodone medicines(oxycontin) for severe pain remedies as it is approved by the FDA. Side Effects of Oxycodone 80mg: The severe side effects of Oxygen 80 mg( oc 80 ) include trouble in respiration and sleep apnoea(that is breathing stops or slows down in sleep) but with time almost every side effect becomes less intense over time. Besides these there are some Common side effects: Dizziness Fatigue Headaches Lightheadedness Low blood pressure Muscle Weakness Physical dependence and some least common side effects are: Abdominal pain Diarrhea Dyspnea Loss of appetite Nervousness Urinary retention Low libido Withdrawal Symptoms Of 80 mg Oxycodone: Withdrawal Symptoms usually occur when/if a patient suddenly tries to stop the dosage of medicine. People using Oxycodone 80 mg for recreational purposes or consuming higher than prescribed amounts are at higher risk of severe withdrawal symptoms. These symptoms are panic attacks, Severe pain, insomnia, weakness in muscles, anxiety, muscle pain, and fever. In many patients, physical dependence has developed due to continuous intake of Oxygen 80mg . It has also been reported that newborns show withdrawal symptoms if their mother has been on an oxycodone prescription. Precaution of Oxygen 80: Oxycodone 80mg is a slightly strong hence dose special needs to be taken care of. Here are some precautions mentioned: In the case of extended release, the remedial impact of the pill should be slower than immediate release so the patient need not swallow the pill directly. It should not be crushed or chewed as it will react instantly. Always taken with water or other fluids. Oxy pills are an opioid, semi-synthetic one, thus they should be consumed only by opioid-tolerant patients. There is a high probability of toxicity due to an overdose of this medicine . Although there is no evidence of pregnancy-related side effects or adverse impacts still it is not advised for pregnant and lactating women. Interaction of Oxycodone 80 mg: Like other medicines, Oxy 80 mg also has some potential interaction tendencies. Few interactions with other medicines can impact health negatively while some are mild. The clearance(excretion from the patient's body) of Oxycodone can be altered by mainly two enzymes namely CYP3A4 and CYP2D6 . These enzymes are responsible for metabolism in the case of Oxycodone 80mg intake. CYP3A4 can increase the half-life of the dose on the other hand, CYP2D6 can decrease the half-life ultimately impacting the potency of the drug. Fosphenytoin reduces the analgesic effects of Oxycodone in chronic pain patients by inducing CYP3A4. Interactions are responsible for impacting various factors like drug metabolism, sedative activities, etc. which are explained further:
